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Chemical Structure| 27282-80-0 Chemical Structure| 27282-80-0

Structure of 27282-80-0

Chemical Structure| 27282-80-0

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Product Details of [ 27282-80-0 ]

CAS No. :27282-80-0
Formula : C4H4Cl2N4
M.W : 179.00
SMILES Code : CNC1=NC(Cl)=NC(Cl)=N1
MDL No. :MFCD02940333

Safety of [ 27282-80-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 27282-80-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 27282-80-0 ]

[ 27282-80-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 593-51-1 ]
  • [ 69125-10-6 ]
  • [ 27282-80-0 ]
YieldReaction ConditionsOperation in experiment
97% With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at -70 - 20℃; for 3.0h; Examples Procedure A Intermediate [1] : [4, 6-DIEHLORO-N-METHYI-L, 3, 5-TRIAZIN-2-AMINE] Cyanuric chloride (10 g, 54.3 mmol, [1] equiv. ) was dissolved in THF (200 mL) and cooled to-70 [C.] DIPEA (36.3 mL, 1.42 mmol, 2 equiv.) and methylamine hydrochloride (3.7g, [1] equiv. ) were added to the reaction mixture, which was stirred 2h at-70 [C] and lh at rt. The THF was removed under reduced pressure and the remaining material was taken up in DCM and washed with water. The organic layer was dried with [MGS04] and the DCM removed to give a colourless powder (9. 5g, 97%). MS [(ESI+)] : 181.2 ; MS (ESI-) : 179.2.
 

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