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Chemical Structure| 25413-27-8 Chemical Structure| 25413-27-8

Structure of 25413-27-8

Chemical Structure| 25413-27-8

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Product Details of [ 25413-27-8 ]

CAS No. :25413-27-8
Formula : C10H13NO2
M.W : 179.22
SMILES Code : O=C(N)CCC1=CC=C(OC)C=C1
MDL No. :MFCD00017149

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Application In Synthesis of [ 25413-27-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 25413-27-8 ]

[ 25413-27-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15893-42-2 ]
  • [ 25413-27-8 ]
YieldReaction ConditionsOperation in experiment
33.4 mg With ammonium hydroxide; In dichloromethane; at 0 - 20℃; for 0.333333h; Step 2 Ammonium hydroxide (0.13 M) was added to a solution of acid chloride (1 eq) in CH2C12 (0.2 M) at 0 C. The reaction mixture stirred for 20 minutes at rt. The reaction mixture was extracted into CH2C12 and the organic layer was dried with Na2S04 and concentrated to give the amide as a white solid in 35% yield over 2 steps, 33.4 mg. 1H NMR (500 MHz, DMSO-d6) δ 7.27 (s, 1H), 7.12 - 7.08 (m, 2H), 6.84 - 6.79 (m, 2H), 6.78 - 6.73 (m, 1H), 3.70 (s, 3H), 2.71 (t, J= 7.7 Hz, 2H), 2.29 (t, J= 7.8 Hz, 2H). ESI-MS (m z): 180.0 [M+H]+.
 

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