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Chemical Structure| 247570-27-0 Chemical Structure| 247570-27-0

Structure of 247570-27-0

Chemical Structure| 247570-27-0

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Product Details of [ 247570-27-0 ]

CAS No. :247570-27-0
Formula : C8H11ClFNO
M.W : 191.63
SMILES Code : NCC1=CC=C(OC)C(F)=C1.[H]Cl
MDL No. :MFCD04116341

Safety of [ 247570-27-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 247570-27-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 247570-27-0 ]

[ 247570-27-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 331-62-4 ]
  • [ 247570-27-0 ]
YieldReaction ConditionsOperation in experiment
89% General procedure: To a solution of ReIO2(PPh3)2 (10 mol %) in toluene (3 mL) were added the nitrile (1 mmol) and PhSiH3 (300 mol %). The reaction mixture was stirred at reflux temperature under air atmosphere and the progress of the reaction was monitored by TLC or 1H NMR. Upon completion, the reaction mixture was cooled to ambient temperature, stirred with charcoal during 3 min and then filtered through a plug of alumina/Celite. To the filtrate was added an ethereal solution of HCl (1.5 mol) to induce the precipitation of amine hydrochloride salts. The solids were isolated upon filtration and then washed with n-hexane to afford the pure amine hydrochloride salts, which are all known compounds.
 

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