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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 24096-63-7 Chemical Structure| 24096-63-7

Structure of 24096-63-7

Chemical Structure| 24096-63-7

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Product Details of [ 24096-63-7 ]

CAS No. :24096-63-7
Formula : C8H5Cl2F3
M.W : 229.03
SMILES Code : FC(C1=CC=C(C(Cl)=C1)CCl)(F)F
MDL No. :MFCD13194728

Safety of [ 24096-63-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H318
Precautionary Statements:P280-P301+P312+P330-P305+P351+P338+P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 24096-63-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 24096-63-7 ]

[ 24096-63-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 56456-51-0 ]
  • [ 24096-63-7 ]
YieldReaction ConditionsOperation in experiment
92% With pyridine; thionyl chloride; In tetrahydrofuran; diethyl ether; at 0 - 30℃; for 15h; To a solution of <strong>[56456-51-0]2-chloro-4-trifluoromethylbenzyl alcohol</strong> (38.8 g) and pyridine (3.0 ml) in diethyl ether (320 ml)- tetrahydrofuran (80 ml) was added thionyl chloride (32.8 g) , and the mixture was stirred at room temperature for 15 hr. The reaction solution was concentrated, water was poured' into the residue and the mixture was extracted with ethyl acetate. The o ethyl acetate layer was washed with IN hydrochloric acid, a saturated aqueous sodium hydrogencarbonate solution and saturated brine, dried (MgSO4), and concentrated. The residue was subjected to silica gel column chromatography, and eluted with ethyl acetate-hexane (1:25 - 1:12, v/v) to give 2-chloro- 4-trifluoromethylbenzyl chloride (38.9 g, yield: 92%) as a colorless oil.1H-NMR (300 MHz, CDCl3) delta:4.72 (2 H,, s) , 7.51 - 7.57 (1 H, m) , 7.60 - 7.70 (2 H, m) .
 

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