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Chemical Structure| 2401-25-4 Chemical Structure| 2401-25-4

Structure of 2401-25-4

Chemical Structure| 2401-25-4

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Product Details of [ 2401-25-4 ]

CAS No. :2401-25-4
Formula : C7H6ClIO
M.W : 268.48
SMILES Code : COC1=CC=C(Cl)C(I)=C1
MDL No. :MFCD00070768
InChI Key :CKEGHWVVAIEDPU-UHFFFAOYSA-N
Pubchem ID :15442946

Safety of [ 2401-25-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 2401-25-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2401-25-4 ]

[ 2401-25-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 89694-46-2 ]
  • [ 2401-25-4 ]
YieldReaction ConditionsOperation in experiment
With chloroamine-T; sodium iodide; In methanol; water; at 20℃; for 0.25h;flask wrapped with aluminum foil; To a 250ml round-bottom flask wrapped with aluminum foil was added a solution of 2-chloro-5- methoxy-phenyl boronic acid (5g, 26.82mmol) in 50percent MeOH/H20 (100ml). A solution of Nal (5.57g, 33.5 mmol) in water (34ml) and a solution of Chloramine-T (18.9g, 67.1mmol) in 50percent MeOH/H20 (34ml) were added to the mixture while stirring. Stirring was continued for 15 min at rt, followed by treatment with water and extraction with diethyl ether. The organic extraction was washed with water and brine, dried over sodium sulfate, filtered and evaporated. The residue was purified by flash chromatography with 10percent EtOAc in hexane to afford the desired product contaminated with EtOAc (8.6g).
 

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