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Chemical Structure| 23120-19-6 Chemical Structure| 23120-19-6

Structure of 23120-19-6

Chemical Structure| 23120-19-6

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Product Details of [ 23120-19-6 ]

CAS No. :23120-19-6
Formula : C10H15N5O2
M.W : 237.26
SMILES Code : NC1=C([N+]([O-])=O)C(NC2CCCCC2)=NC=N1

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Application In Synthesis of [ 23120-19-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 23120-19-6 ]

[ 23120-19-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4316-94-3 ]
  • [ 108-91-8 ]
  • [ 23120-19-6 ]
YieldReaction ConditionsOperation in experiment
92.2% With tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In acetonitrile; at 25℃; for 3.5h;Inert atmosphere; General procedure: 6-Chloro-5-nitropyrimidine-4-amine (0.5mmol), amine (1.5mmol), Pd2(dba)3 (0.01mmol), R-BINAP (0.03mmol) and potassium carbonate (0.7mmol) were dissolved in acetonitrile (5mL). The solution was stirred at room temperature for 3.5h under an argon atmosphere. The resulting reaction mixture was treated with saturated brines (50mL) and extracted with acetonitrile (3×25mL), and dried with anhydrous Na2SO4. The anhydrous Na2SO4 was removed by filtration and the filtrate was concentrated. The residue was washed with ethyl acetate (3×2mL) and diethyl ether (3×2mL), filtered and dried under vacuum.
 

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