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Chemical Structure| 2287-10-7 Chemical Structure| 2287-10-7

Structure of 2287-10-7

Chemical Structure| 2287-10-7

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Product Details of [ 2287-10-7 ]

CAS No. :2287-10-7
Formula : C13H18N2O4
M.W : 266.29
SMILES Code : O=[N+](C1=CC=C(OCCN2CCCC2)C(OC)=C1)[O-]
MDL No. :MFCD17015367

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Application In Synthesis of [ 2287-10-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2287-10-7 ]

[ 2287-10-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2955-88-6 ]
  • [ 454-16-0 ]
  • [ 2287-10-7 ]
YieldReaction ConditionsOperation in experiment
54.19% With caesium carbonate; In N,N-dimethyl-formamide; at 90℃; for 2h; To a stirred solution of <strong>[454-16-0]1-fluoro-2-methoxy-4-nitrobenzene</strong> (ig, 5.84mmole) in DMF (lOmI) was added Cs2CO3 (2.85g, 8.76mmole) and 2-(pyrrolidin-1 -yl)ethan-1 -ol (807mg, 7.01 2mmole). The reaction mixture was stirred for 2hrs at 90°C. Water (25m1) was added and the crude product was extracted with ethyl acetate (25m1 x 3). Combined organic layers were washed with brine (25m1 x 3), dried over sodium sulfate and evaporated under vacuum to get crude material. The obtained crude was purified by flash chromatography to get pure title compound (840mg, Yield:54.19percent).LCMS: 99.65percent ESI-MS (m/z): 266.97 [M+1].
 

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