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Chemical Structure| 21636-51-1 Chemical Structure| 21636-51-1

Structure of 21636-51-1

Chemical Structure| 21636-51-1

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Product Details of [ 21636-51-1 ]

CAS No. :21636-51-1
Formula : C7H9NO2
M.W : 139.15
SMILES Code : OCC1=CC(CO)=CN=C1
MDL No. :MFCD11617170
InChI Key :HYUQKAGYJAFMBA-UHFFFAOYSA-N
Pubchem ID :20184985

Safety of [ 21636-51-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 21636-51-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 21636-51-1 ]

[ 21636-51-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4591-55-3 ]
  • [ 21636-51-1 ]
YieldReaction ConditionsOperation in experiment
20% With methanol; sodium tetrahydroborate; calcium chloride; at 50℃; for 5h; Compound ll (3.00 g, 17.95 mmol) was added to a solution of Sodium borohydride (0.81 g, 21.54 mmol) and calcium chloride (3.16 g, 21.54 mmol) were placed in methanol (200 mL), followed by stirring at 50 C for 5 hours. After the reaction was completed, the solvent was completely removed under reduced pressure, and a saturated aqueous solution of potassium carbonate (100 ml) was added thereto. The mixture was stirred at 100 C for 1 hour and slowly cooled to room temperature. Filtered, and then purified by column chromatography (methanol: dichloromethane = 0.5: 9.5) to obtain 0.5 g (20%) of compound 12 was obtained.
 

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