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Chemical Structure| 205194-11-2 Chemical Structure| 205194-11-2

Structure of 205194-11-2

Chemical Structure| 205194-11-2

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Product Details of [ 205194-11-2 ]

CAS No. :205194-11-2
Formula : C7H15NO
M.W : 129.20
SMILES Code : OC[C@H]1CN(C)CCC1
MDL No. :MFCD11035735
InChI Key :UGXQXVDTGJCQHR-SSDOTTSWSA-N
Pubchem ID :920113

Safety of [ 205194-11-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis of [ 205194-11-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 205194-11-2 ]

[ 205194-11-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5166-67-6 ]
  • [ 205194-11-2 ]
YieldReaction ConditionsOperation in experiment
94% With sodium hydroxide; In tetrahydrofuran; water; A solution of (R)-<strong>[5166-67-6]ethyl 1-methylpiperidine-3-carboxylate</strong> (5.69 g, 33 mmol) in ether (20 ml) was added dropwise to a stirred solution of lithium aluminum hydride (36.6 ml of a 1M solution in THF, 36.6 mmol) in ether (85 ml) cooled to maintain a reaction temperature of 20 C. The mixture was stirred for 1.5 hours at ambient temperature and then water (1.4 ml), 15% aqueous sodium hydroxide solution (1.4 ml) and then water (4.3 ml) were added. The insolubles were removed by filtration and the volatiles removed from the filtrate by evaporation to give (R)-(1-methylpiperidin-3-yl)methanol (4.02 g, 94%) as a colourless oil. 1H NMR Spectrum: (DMSOd6) 1.06(q, 1H); 1.51-1.94(m, 5H); 2.04(s, 3H); 2.34(br s. 1H); 2.62(m, 1H); 2.78(d, 1H); 3.49(m, 1H); 3.59(m. 1H); MS-ESI: 130 [MH]+.
 

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[ 205194-11-2 ]

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