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Chemical Structure| 203664-03-3 Chemical Structure| 203664-03-3

Structure of 203664-03-3

Chemical Structure| 203664-03-3

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Product Details of [ 203664-03-3 ]

CAS No. :203664-03-3
Formula : C6H9N3O
M.W : 139.16
SMILES Code : CC(NCC1=NC=CN1)=O

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Application In Synthesis of [ 203664-03-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 203664-03-3 ]

[ 203664-03-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 22600-77-7 ]
  • [ 203664-03-3 ]
YieldReaction ConditionsOperation in experiment
With pyridine; acetic anhydride; In N,N-dimethyl-formamide; Production Example 160 N-(Imidazol-2-ylmethyl)acetamide 0.34 g of <strong>[22600-77-7]2-aminomethylimidazole dihydrochloride</strong> was added to 20 ml of N,N-dimethylformamide in a nitrogen atmosphere. Under ice-cooling, 0.40 g of sodium hydride (60% oily) was added thereto and the resulting mixture was subjected to ultrasonication for 30 minutes. To the reaction mixture were added 20 ml of pyridine and 10 ml of acetic anhydride and the obtained mixture was stirred at room temperature for 2 days. After concentrating under reduced pressure, the residue was distributed into water and ethyl acetate. The organic layer was washed with water and dried over anhydrous sodium sulfate. The extract was concentrated under reduced pressure to thereby give 0.24 g of the title compound as a pale brown solid. 1H-NMR(CDCl3) delta ppm: 1.99(s, 3H), 4.44(d, J=7 Hz, 2H), 6.96(s, 2H), 8.25(br.s, 1H), 8.39(br.m, 1H)
 

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