Home Cart Sign in  
Chemical Structure| 201601-50-5 Chemical Structure| 201601-50-5

Structure of 201601-50-5

Chemical Structure| 201601-50-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 201601-50-5 ]

CAS No. :201601-50-5
Formula : C17H29NO2Si
M.W : 307.50
SMILES Code : CC(C)(C)[Si](C)(C)O[C@H]1CN(CC2=CC=CC=C2)C[C@@H]1O

Safety of [ 201601-50-5 ]

Application In Synthesis of [ 201601-50-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 201601-50-5 ]

[ 201601-50-5 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 90365-74-5 ]
  • [ 18162-48-6 ]
  • [ 201601-50-5 ]
YieldReaction ConditionsOperation in experiment
35% With 1H-imidazole; In N,N-dimethyl-formamide; at 20℃; To a stirred solution of <strong>[90365-74-5](3S,4S)-1-benzyl-3,4-dihydroxypyrrolidine</strong> (1.00 g, 5.2 mmol) and 0 imidazole (0.71 g, 10.4 mmol) in DMF (10 mL) was added t-butyldimethylsilyl chloride (0.47 g, 3.1 mmol). The solution was stirred overnight at rt, diluted with Et2O (80 mL) and washed with water (2 x 35 mL). The combined water washes were back extracted with Et2O (30 mL). The combined Et2O layers were washed with brine (10 mL), dried over MgSO4 and concentrated to leave an oil (0.85 g). The crude product was applied to a 12-g silica cartridge and eluted with a 0-100% EtOAc 5 in hexanes gradient to afford (3S,4S)-1-benzyl-3-hydroxy-4-(t-butyldimethyI-silyloxy)pyrrolidine (0.56 g, 35%)
 

Historical Records