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Chemical Structure| 199863-73-5 Chemical Structure| 199863-73-5

Structure of 199863-73-5

Chemical Structure| 199863-73-5

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Product Details of [ 199863-73-5 ]

CAS No. :199863-73-5
Formula : C8H11N3O
M.W : 165.19
SMILES Code : OC1=NC(N)=NC(C2CCC2)=C1
MDL No. :MFCD20702090

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Application In Synthesis of [ 199863-73-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 199863-73-5 ]

[ 199863-73-5 ] Synthesis Path-Downstream   1~1

  • 1
  • guanidine hydrochloride salt [ No CAS ]
  • [ 137638-05-2 ]
  • [ 199863-73-5 ]
YieldReaction ConditionsOperation in experiment
To a solution of methyl S-cyclobutyl-S-oxopropanoate (6.5 g, 41.6 mmol) and guanidine hydrochloride (4.77 g, 49.9 mmol) in CH3OH (80 ml.) at room temperature was added potassium te/t-butoxide (25.2 g) portionwise over 15 minutes with vigorous stirring and the reaction warmed automatically. Then the reaction was cooled to room temperature and stirred overnight. The precipitated salt was removed by filtration, and the filtrate was concentrated under reduce pressure to approximately 10 ml_, then diluted with 10 ml. of water and the pH adjusted to 5 by the addition of 6N HCI. The precipitate was separated by filtration to afford the title compound (6.6 g) as a white solid. 1H NMR: δ 10.647 (br, 1H), 6.5 (br, 2 H), 5.35 (s, 1 H), 3.11-3.20 (m, 1 H), 1.86-2.13 (m, 4 H), 1.71-1.77 (m, 2 H).
 

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