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Chemical Structure| 196959-50-9 Chemical Structure| 196959-50-9

Structure of 196959-50-9

Chemical Structure| 196959-50-9

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Product Details of [ 196959-50-9 ]

CAS No. :196959-50-9
Formula : C14H11ClN2O
M.W : 258.70
SMILES Code : COC1=CN2C(C=C1)=NC(C3=CC=C(Cl)C=C3)=C2
MDL No. :MFCD30536477

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Application In Synthesis of [ 196959-50-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 196959-50-9 ]

[ 196959-50-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10167-97-2 ]
  • [ 536-38-9 ]
  • [ 196959-50-9 ]
YieldReaction ConditionsOperation in experiment
With sodium hydrogencarbonate; 6.1. 2-(4-Chlorophenyl)-6-methoxyimidazo[1,2-a]pyridine A mixture of 1.3 g (10.5 mmol) of 5-methoxy-2-pyridinamine, 2.44 g (1eq) of alpha-bromo-4-chloroacetophenone and 1.76 g (2eq) of sodium bicarbonate in 20 ml of 95percent strength alcohol is heated under reflux for 4 h 30 min. under argon. The mixture is evaporated to dryness and the residue taken up between CH2 Cl2 and H2 O, followed by washing, drying and evaporation. The product is purified by chromatography and then crystallized in ether. M.p. 148°-9° C. 5-Methoxy-2-pyridinamine was obtained according to a process described in the literature: G. J. Clark and L. W. Deady, Aust. J. Chem. 34, 927 (1981).
 

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