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Chemical Structure| 191731-36-9 Chemical Structure| 191731-36-9

Structure of 191731-36-9

Chemical Structure| 191731-36-9

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Product Details of [ 191731-36-9 ]

CAS No. :191731-36-9
Formula : C7H11N3O2
M.W : 169.18
SMILES Code : O=C(N(OC)C)CN1C=CN=C1
MDL No. :MFCD22414356

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Application In Synthesis of [ 191731-36-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 191731-36-9 ]

[ 191731-36-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 288-32-4 ]
  • [ 67442-07-3 ]
  • [ 191731-36-9 ]
YieldReaction ConditionsOperation in experiment
37% In tetrahydrofuran; methanol; chloroform; 1. 2-Imidazol-1-yl-N-methoxy-N-methyl-acetamide 60percent sodium hydride in oil (0.296 g, 7.4 mol) was washed with tetrahydrofuran and suspended in additional tetrahydrofuran (10 ml). To this was added imidazole (0.506 g, 7.43 mol) followed by stirring at 25° C. for 1 hour. To the mixture was added a solution of <strong>[67442-07-3]2-chloro-N-methoxy-N-methyl-acetamide</strong> (1.02 g, 7.4 mmol, prepared per Tetrahedron Letters Vol. 30, No. 29, pp3779-80, 1989.) followed by stirring at 25° C. for 15. The mixture was filtered, and the filtrate was evaporated to an oil in vacuo and purifide by chromatography on silica gel eluted with a gradient of chloroform to 10percent methanol:chloroform giving a solid 0.46 g, 37percent yield.
 

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