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Chemical Structure| 190967-63-6 Chemical Structure| 190967-63-6

Structure of 190967-63-6

Chemical Structure| 190967-63-6

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Product Details of [ 190967-63-6 ]

CAS No. :190967-63-6
Formula : C15H21NO3
M.W : 263.33
SMILES Code : O=C(N1[C@H](CCO)CCCC1)OCC2=CC=CC=C2
MDL No. :MFCD28008408

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Application In Synthesis of [ 190967-63-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 190967-63-6 ]

[ 190967-63-6 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 13139-17-8 ]
  • [ 103639-57-2 ]
  • [ 190967-63-6 ]
YieldReaction ConditionsOperation in experiment
PREPARATION 2 N-Benzyloxycarbonyl-2(S)-(2-hydroxyethyl)piperidine To a stirred, ice-cooled solution of the title compound of Preparation 1 (13.4 g, 0.104 mol) in dichloromethane (250 ml) were added, sequentially, triethylamine (15.9 ml, 0.114 mol) and N-(benzyloxycarbonyloxy)succinimide (27.21 9, 0.109 mol). The cooling bath was removed, then the reaction mixture stirred at room temperature for 18 hours, washed with brine, dried (Na2 SO4) and evaporated under reduced pressure to give an oil (30.6 g) which was purified by chromatography on silica gel, using hexane:ethyl acetate (1:1) as eluant, to provide the title compound (27.5 g) as an oil. Rf 0.48 (SS 2). [alpha]D25 -24.5° (c=1.06, CH3 OH).
  • 3
  • [ 501-53-1 ]
  • [ 103639-57-2 ]
  • [ 190967-63-6 ]
 

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