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Chemical Structure| 180003-61-6 Chemical Structure| 180003-61-6

Structure of 180003-61-6

Chemical Structure| 180003-61-6

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Product Details of [ 180003-61-6 ]

CAS No. :180003-61-6
Formula : C17H17N
M.W : 235.32
SMILES Code : CC1(C)C(C)=NC2=C1C=CC(C3=CC=CC=C3)=C2

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Application In Synthesis of [ 180003-61-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 180003-61-6 ]

[ 180003-61-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 563-80-4 ]
  • [ 109221-88-7 ]
  • [ 180003-61-6 ]
  • 2,3,3-Trimethyl-4-phenyl-3H-indole [ No CAS ]
  • 2
  • [ 563-80-4 ]
  • [ 109221-88-7 ]
  • [ 180003-61-6 ]
YieldReaction ConditionsOperation in experiment
In acetic acid; Example 3 Synthesis of 6-phenyl-2,3,3-trimethylindolenine (3) The following compound is prepared: STR28 A mixture of <strong>[109221-88-7]3-hydrazinobiphenyl hydrochloride</strong> (72 g, 0.32 mol) and 3-methyl-2-butanone (35 mL, 0.32 mol) in glacial acetic acid (300 mL) is stirred at 110 C. for 1.5 hours. The solution is then cooled to room temperature, and filtered to remove the insoluble ammonium chloride salt. The filtrate is concentrated to 1/3 of its volume and then poured into H2 O (1 L). The product is extracted with EtOAc (4*200 mL). The combined EtOAc solution is neutralized with saturated NaHCO3 and washed with H2 O (200 mL) and brine (200 mL). After drying over anhydrous Na2 SO4, removal of solvent gives 20 g of brown oil. The product is further purified by vacuum distillation.
 

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