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Chemical Structure| 17880-34-1 Chemical Structure| 17880-34-1

Structure of 17880-34-1

Chemical Structure| 17880-34-1

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Product Details of [ 17880-34-1 ]

CAS No. :17880-34-1
Formula : C9H9NO4
M.W : 195.17
SMILES Code : O=C(C1=NC=C(C(OCC)=O)C=C1)O
MDL No. :MFCD00461304

Safety of [ 17880-34-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 17880-34-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17880-34-1 ]

[ 17880-34-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5552-44-3 ]
  • [ 17880-34-1 ]
YieldReaction ConditionsOperation in experiment
69% 5-(Ethoxycarbonyl)picolinic acid (5.4)To a stirring solution of <strong>[5552-44-3]diethyl pyridine-2,5-dicarboxylate</strong> (3.49 g, 15.6 mmol) in ethanol (31 ml) was added sodium hydroxide pellets (0.66 g, 16.6 mmol). The reaction was heated at reflux for 4 h. The reaction was quenched with 2M HCI (1 1 mL) at the reflux temperature, allowed to cool to room temperature and then 0 C. The resulting precipitate was filtered, washed with ethanol (25 mL) and dried with heating under vacuum to afford the mono-acid as a white free flowing powder (2.1 g, 69%). 1 H NMR (400MHz CDCI3) δΗ ppm 1 .25 (t, 3H), 4.35 (q, 2H), 8.15 (d, 2H), 8.46 (d, 2H), 9.18 (s, 1 H).
 

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