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Chemical Structure| 167486-39-7 Chemical Structure| 167486-39-7

Structure of 167486-39-7

Chemical Structure| 167486-39-7

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Product Details of [ 167486-39-7 ]

CAS No. :167486-39-7
Formula : C22H29NO4
M.W : 371.47
SMILES Code : O=C(OC(C)(C)C)NC(COCC1=CC=CC=C1)COCC2=CC=CC=C2
MDL No. :MFCD29917053

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Application In Synthesis of [ 167486-39-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 167486-39-7 ]

[ 167486-39-7 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 100-39-0 ]
  • [ 125414-41-7 ]
  • [ 167486-39-7 ]
YieldReaction ConditionsOperation in experiment
45% With potassium hydroxide; In N,N-dimethyl-formamide; for 2h; tert-Butyl (l,3-dihydroxypropan-2-yl)carbamate (3.7 g, 19.35 mmol), potassium hydroxide (4.0 g, 71.59 mmol), and benzyl bromide (12.24 g, 71.59 mmol) were dissolved in 50 mL of DMF. The mixture was stirred for 2 h and concentrated under vacuum. The crude product was purified using column chromatography to yield tert-butyl (1 ,3-bis(benzyloxy)propan-2- yl)carbamate (3.25 g, 45% yield).
  • 2
  • [ 144570-06-9 ]
  • [ 865-47-4 ]
  • [ 100-39-0 ]
  • [ 125414-41-7 ]
  • [ 167486-39-7 ]
YieldReaction ConditionsOperation in experiment
49% In tetrahydrofuran; STEP B N-TERT-BUTOXYCARBONYL-DI(O-BENZYL)SERINOL The title compound was prepared in 49% yield from N-tert-butoxycarbonyl serinol using the procedure given in Example 4, Step B, but using tetrahydrofuran as solvent, 2.4 equivalents of benzyl bromide and 2.2 equivalents of potassium-tert-butoxide. RF: 0.17 (silica gel, petroleum ether/ethyl acetate: 90/10).
  • 3
  • [ 79069-15-1 ]
  • [ 100-39-0 ]
  • [ 167486-39-7 ]
 

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