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Chemical Structure| 1632154-29-0 Chemical Structure| 1632154-29-0

Structure of 1632154-29-0

Chemical Structure| 1632154-29-0

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Product Details of [ 1632154-29-0 ]

CAS No. :1632154-29-0
Formula : C11H8ClN3S
M.W : 249.72
SMILES Code : CC1=C(C2=CC=C(Cl)C=C2)SC3=NC=NN31
MDL No. :MFCD27991815

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Application In Synthesis of [ 1632154-29-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1632154-29-0 ]

[ 1632154-29-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 34179-62-9 ]
  • [ 14752-66-0 ]
  • [ 1632154-29-0 ]
YieldReaction ConditionsOperation in experiment
81% With copper diacetate; palladium diacetate; In 1,4-dioxane; diethylene glycol dimethyl ether; at 120℃; for 24h; General procedure: A reaction vessel was charged with thiazolo[3,2-b]-1,2,4-triazoles 1 (0.5 mmol), sodium arylsulfinates 2 (1 mmol),Pd(OAc)2 (5 mol%), Cu(OAc)2 (2 equiv), and dioxane-diglyme (1:2; 1 mL). The mixture was stirred at 120 C andmonitored by TLC. After the completion of the reaction, themixture was poured into H2O (10 mL), and extracted withEtOAc (3 × 10 mL). The combined extract was dried withanhyd MgSO4. The solvent was removed and the crudeproduct was separated by column chromatography (elutedwith petroleum ether-EtOAc) to give the desired products 3and 4.
 

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