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Chemical Structure| 1620494-29-2 Chemical Structure| 1620494-29-2

Structure of 1620494-29-2

Chemical Structure| 1620494-29-2

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Product Details of [ 1620494-29-2 ]

CAS No. :1620494-29-2
Formula : C33H32N4O5
M.W : 564.63
SMILES Code : O=C(OCC)C1=NN(C2=CC=C(OCC=3C=CC=CC3)C=C2)C=4C(=O)N(C5=CC=C(C=C5)N6C(=O)CCCC6)CCC14
MDL No. :N/A

Safety of [ 1620494-29-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H372
Precautionary Statements:P260-P264-P270-P314-P501

Application In Synthesis of [ 1620494-29-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1620494-29-2 ]

[ 1620494-29-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 545445-44-1 ]
  • [ 1620494-28-1 ]
  • [ 1620494-29-2 ]
YieldReaction ConditionsOperation in experiment
54 mg With triethylamine; potassium iodide; In ethyl acetate; at 25 - 80℃; In a clean round bottomed flask ethyl acetate (525ml), ethyl (2Z)-[4-(benzyloxy)phenyl]hydrazono}(chloro)acetate (35gm), potassium iodide (1.73 g), 3-morpholino-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydropyridin-2(1H)-one (31.82g) and triethylamine (42.63g) were added at about 25-30C . The reaction mass was heated to about 75-80C for about 10-15 hrs. After completion, the reaction, mass was cooled to about 0 - 5C and dilute hydrochloric acid was added slowly to the reaction mass. The temperature of the reaction mass was raised to about 25-30C and stirred for 5-7 hrs. Ethyl acetate and water were added to the reaction mass and stirred for 15 min. The layers were separated and the organic layer was washed with aq. sodium carbonate solution followed by water and brine solution. The organic layer was concentrated under vacuum and cooled to about 25-30C. Di isopropyl ether was added to the reaction mass and stirred for 1 hr. The precipitated solid was filtered and washed with di isopropyl ether. The solid was dried under vacuum at 45-50C for 12hrs to obtain 54gm of 1-(4-benzyloxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1- yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester.
 

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