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Chemical Structure| 1613335-09-3 Chemical Structure| 1613335-09-3

Structure of 1613335-09-3

Chemical Structure| 1613335-09-3

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Product Details of [ 1613335-09-3 ]

CAS No. :1613335-09-3
Formula : C14H8FNOS
M.W : 257.28
SMILES Code : N#CC1=CC=C(SC2=CC=C(F)C=C2)C(C=O)=C1
MDL No. :MFCD31915920

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Application In Synthesis of [ 1613335-09-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1613335-09-3 ]

[ 1613335-09-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 371-42-6 ]
  • [ 146137-79-3 ]
  • [ 1613335-09-3 ]
YieldReaction ConditionsOperation in experiment
97% With potassium carbonate; In N,N-dimethyl-formamide; at 70℃; for 18h; 3-formyl-4-(4-fluorophenylthio)benzonitrile In a 50 mL round-bottomed flask, <strong>[146137-79-3]4-fluoro-3-formylbenzonitrile</strong> (900 mg, 5.73 mmol) and potassium carbonate (872 mg, 6.31 mmol) were suspended in DMF (10 mL) to give a yellow suspension. Then 4-fluorobenzenethiol (0.654 mL, 6.02 mmol) was added and the reaction mixture heated at 70°C for 18h. The reaction mixture was poured into water. The solid was filtered, washed with water and with a few amount of DIPE then dried in vacuo to give 1.44g of a pale yellow solid (Yield : 97percent) APCI-MS: (M+H)+ =257 1H NMR (300 MHz, DMSO-d6) delta ppm: 10.12 (s, 1H), 8.49 (d, J = 1.9 Hz, 1H), 7.85 (dd, J = 8.5, 2.0 Hz, 1H), 7.71 - 7.62 (m, 2H), 7.43 (ddd, J = 10.9, 6.0, 2.6 Hz, 2H), 6.80 (d, J = 8.5 Hz, 1H).
 

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