Home Cart Sign in  
Chemical Structure| 1572048-45-3 Chemical Structure| 1572048-45-3

Structure of 1572048-45-3

Chemical Structure| 1572048-45-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1572048-45-3 ]

CAS No. :1572048-45-3
Formula : C10H10Cl2N2O4
M.W : 293.10
SMILES Code : COC1=C(Cl)N=C(Cl)N=C1OC2(C(OC)=O)CC2
MDL No. :MFCD29053468

Safety of [ 1572048-45-3 ]

Application In Synthesis of [ 1572048-45-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1572048-45-3 ]

[ 1572048-45-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 33689-29-1 ]
  • [ 60703-46-0 ]
  • [ 1572048-45-3 ]
YieldReaction ConditionsOperation in experiment
100% With sodium hydride; In tetrahydrofuran; mineral oil; at -78 - 20℃; for 2h; To a solution of 2,4,6-trichloro-5-methoxy-pyrimidine (213 mg, 1.00 mmol) and <strong>[33689-29-1]1-hydroxy-cyclopropanecarboxylic acid methyl ester</strong> (139 mg, 1.20 mmol) in THF (4 mL) was added sodium hydride (48 mg, 1.20 mmol, 60% dispersion in mineral oil) at -78 C. The resulting mixture was allowed to warm to RT and stirred for 2 hours. The reaction mixture was quenched with saturated aqueous ammonium chloride solution and extracted with ethyl acetate. The combined organic extracts were dried (Na2SO4) and concentrated in vacuo affording 1-(2,6-Dichloro-5-methoxy-pyrimidin-4-yloxy)-cyclopropanecarboxylic acid methyl ester as a white solid (300 mg, quantitative). LCMS: RT=3.49 min, [M+H]+=341/343/345.
 

Historical Records