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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 154321-32-1 Chemical Structure| 154321-32-1

Structure of 154321-32-1

Chemical Structure| 154321-32-1

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Product Details of [ 154321-32-1 ]

CAS No. :154321-32-1
Formula : C6H4Br3N
M.W : 329.81
SMILES Code : BrC(C1=CN=C(Br)C=C1)Br
MDL No. :MFCD21496459

Safety of [ 154321-32-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 154321-32-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 154321-32-1 ]

[ 154321-32-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 3510-66-5 ]
  • [ 101990-45-8 ]
  • [ 154321-32-1 ]
YieldReaction ConditionsOperation in experiment
With bromine; In dichloromethane; water; for 0.5h;Heating / reflux; Generally, to a refluxing mixture of 2-bromo-methyl-pyridine (5 g, 29 mmol) in a biphasic medium of DCM (500 ml) and water (500 ml) was added Br2 (1.65 ml, 31.9 mmol). The mixture was illuminated using a halogen lamp (500 W, distance: 5-10 cm) under reflux for 30 min. The solution was cooled to room temperature and neutralized with a 10% Na2CO3 aqueous solution and solid NaCl was added. The aqueous layer was extracted three times with DCM, the combined organic extracts were dried over MgSO4 and evaporated in vacuo. HPLC analysis of the crude product showed the relative ratio of 13.6:76.5:9.9 (Retention time: 8.1, 10.6 and 13.4 min, respectively) for starting material 2-bromo-methyl-pyridine:2-bromo-5-(bromomethyl)pyridine: 2-bromo-5-(dibromomethyl)pyridine.
  • 2
  • [ 3510-66-5 ]
  • 2-bromo-5-tribromomethyl-pyridine [ No CAS ]
  • [ 101990-45-8 ]
  • [ 154321-32-1 ]
 

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