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Chemical Structure| 1430845-64-9 Chemical Structure| 1430845-64-9

Structure of 1430845-64-9

Chemical Structure| 1430845-64-9

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Product Details of [ 1430845-64-9 ]

CAS No. :1430845-64-9
Formula : C20H31BN2O2
M.W : 342.28
SMILES Code : CC(C)(C(C)(C)O1)OB1C2=CN(CC34CC5CC(C4)CC(C3)C5)N=C2

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Application In Synthesis of [ 1430845-64-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1430845-64-9 ]

[ 1430845-64-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 269410-08-4 ]
  • [ 14651-42-4 ]
  • [ 1430845-64-9 ]
YieldReaction ConditionsOperation in experiment
With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 70℃; Example 1A 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-pyrazole A mixture of <strong>[14651-42-4]1-(bromomethyl)adamantane</strong> (0.458 g) and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (0.377 g) in N,N-dimethylformamide (5 mL) was cooled to 0 C. To this solution was added 60% sodium hydride (0.096 g). The solution was heated at 70 C. overnight. The reaction mixture was partitioned between water and ethyl acetate. The aqueous layer was extracted with additional ethyl acetate twice. The combined organic layers were washed with brine, dried over MgSO4, filtered, and concentrated. The residue was purified by flash column chromatography on silica gel eluting with 25% ethyl acetate in hexanes to provide the title compound.
 

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