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Chemical Structure| 1420623-75-1 Chemical Structure| 1420623-75-1

Structure of 1420623-75-1

Chemical Structure| 1420623-75-1

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Product Details of [ 1420623-75-1 ]

CAS No. :1420623-75-1
Formula : C9H9N3O2
M.W : 191.19
SMILES Code : O=C(C1=CN=C2C=CC=NN21)OCC
MDL No. :MFCD26407226
InChI Key :VXKOJJIHJFBXSC-UHFFFAOYSA-N
Pubchem ID :71744070

Safety of [ 1420623-75-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1420623-75-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1420623-75-1 ]

[ 1420623-75-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5469-70-5 ]
  • [ 33142-21-1 ]
  • [ 1420623-75-1 ]
YieldReaction ConditionsOperation in experiment
40.8% In ethanol;Reflux; A mixture of pyridazin-3 -amine (9.51 g, 0.1 mol) and 2- <strong>[33142-21-1]ethyl 2-chloro-3-oxopropanoate</strong> (22.5 g,0.15 mol) in EtOH (20 mL) was stirred at reflux overnight. The mixture was allowed to cool to RT and concentrated in vacuo to remove EtOH. The residue was partitioned between water (100 mL) and ethyl acetate (100 mL). The organic layer was separated. The aqueous layer was extracted with ethyl acetate (2 x 50 mL). The combined organic layers were washed with brine, dried over Na2S04 and filtered. The filtrate was concentrated in vacuo. The residue was slurried in isopropyl ether (50 mL) with stirring for 30 min, collected by filtration and dried in vacuo to afford ethyl imidazo[l,2-b]pyridazine-3-carboxylate (7.8 g, 40.8% yield).
 

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