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Chemical Structure| 139191-85-8 Chemical Structure| 139191-85-8

Structure of 139191-85-8

Chemical Structure| 139191-85-8

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Product Details of [ 139191-85-8 ]

CAS No. :139191-85-8
Formula : C15H13NO3
M.W : 255.27
SMILES Code : O=C(OC)C1=CC=CC(C(NC2=CC=CC=C2)=O)=C1
MDL No. :MFCD00963871

Safety of [ 139191-85-8 ]

Application In Synthesis of [ 139191-85-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 139191-85-8 ]

[ 139191-85-8 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 13531-48-1 ]
  • [ 114-83-0 ]
  • [ 38604-74-9 ]
  • [ 139191-85-8 ]
  • 2
  • [ 13531-48-1 ]
  • [ 59-88-1 ]
  • [ 139191-85-8 ]
YieldReaction ConditionsOperation in experiment
With tert.-butylnitrite; iodine; In neat (no solvent); at 25℃; for 6h;Inert atmosphere; General procedure: To a round-bottom flask (25 mL) was added phenylhydrazine hydrochloride 1a (43 mg, 0.3 mmol), benzonitrile 2a (0.3 mL, 3 mmol), t-BuONO (53 muL, 0.45 mmol), I2 (38 mg, 0.15 mmol), the mixture was well stirred for 6 h at 25 oC (the whole process was closely monitored by TLC). Then the reaction mixture was purified by a flash silica gel column chromatography (eluent: Petroleum ether (PE)/Ethyl acetate (EA) = 10:1) to give N-phenylbenzamide 3a as a white solid (38 mg, 64percent).
  • 3
  • [ 13531-48-1 ]
  • [ 59-88-1 ]
  • N-(2-nitrophenyl)-3-(methoxycarbonyl)benzamide [ No CAS ]
  • [ 139191-85-8 ]
YieldReaction ConditionsOperation in experiment
15%; 34% With tert.-butylnitrite; iodine; In neat (no solvent); at 25℃; for 6h; General procedure: To a round-bottom flask (25 mL) was added phenylhydrazine hydrochloride 1a (43 mg, 0.3 mmol), benzonitrile 2a (0.3 mL, 3 mmol), t-BuONO (53 muL, 0.45 mmol), I2 (38 mg, 0.15 mmol), the mixture was well stirred for 6 h at 25 oC (the whole process was closely monitored by TLC). Then the reaction mixture was purified by a flash silica gel column chromatography (eluent: Petroleum ether (PE)/Ethyl acetate (EA) = 10:1) to give N-phenylbenzamide 3a as a white solid (38 mg, 64percent).
 

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