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Chemical Structure| 1379337-67-3 Chemical Structure| 1379337-67-3

Structure of 1379337-67-3

Chemical Structure| 1379337-67-3

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Product Details of [ 1379337-67-3 ]

CAS No. :1379337-67-3
Formula : C9H9IO3
M.W : 292.07
SMILES Code : O=C(C1C(I)=CC=CC=1OC)OC
MDL No. :MFCD18905159

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Application In Synthesis of [ 1379337-67-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1379337-67-3 ]

[ 1379337-67-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 141-53-7 ]
  • [ 146014-66-6 ]
  • [ 1379337-67-3 ]
YieldReaction ConditionsOperation in experiment
77% In methanol; dimethyl sulfoxide; at 80℃;Inert atmosphere; A dry and argon-flushed Schlenck-tube equipped with a magnetic stirrer and a septum was charged with a solution of 3 (1.0 g, 3.57 mmol) in dimethylsulfoxide (4 mL) and a solution of sodium methanoate in methanol (5.4 M, 1mL, 5.4 mmol) was added dropwise. The reaction mixture was stirred overnight at 80 C and was hydrolysed with water (20 mL). The mixture was extracted with EtOAc (3 x 30 mL), the organic phases were combined, washed with water (3 x 50 mL), brine (50 mL), dried over MgSO4, filtered and the solvent was evaporated under reduced pressure to afford the ester 5 (800 mg, 77%) as yellow oil.
 

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