Structure of Delavirdine
CAS No.: 136817-59-9
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Delavirdine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI).
Synonyms: U 90152; BHAP-U 90152
4.5
*For Research Use Only !
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 136817-59-9 |
Formula : | C22H28N6O3S |
M.W : | 456.56 |
SMILES Code : | CS(=O)(NC1=CC2=C(NC(C(N3CCN(C4=NC=CC=C4NC(C)C)CC3)=O)=C2)C=C1)=O |
Synonyms : |
U 90152; BHAP-U 90152
|
MDL No. : | MFCD00871405 |
InChI Key : | WHBIGIKBNXZKFE-UHFFFAOYSA-N |
Pubchem ID : | 5625 |
GHS Pictogram: | ![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00197145 | Infection, Human Immunodeficie... More >>ncy Virus I Less << | Phase 3 | Terminated | - | - |
NCT02016924 | Acquired Immune Deficiency Syn... More >>drome (AIDS) HIV Infections Less << | Phase 2 Phase 3 | Recruiting | December 2024 | United States, California ... More >> Pediatric Infectious Diseases Associate Recruiting Long Beach, California, United States, 90806 Principal Investigator: Jagmohan Batra, MD Children's Hospital Los Angeles Withdrawn Los Angeles, California, United States, 90027 United States, Colorado Children's Hospital Colorado Recruiting Aurora, Colorado, United States, 80045 Principal Investigator: Elizabeth McFarland, MD United States, District of Columbia Children's National Medical Center Recruiting Washington, District of Columbia, United States, 20852 Principal Investigator: Natella Rakhmanina United States, Florida University of South Florida Clinic at Children's Medical Services Recruiting Tampa, Florida, United States, 33620 Principal Investigator: Carina Rodriguez, MD United States, Georgia Emory-Children's Center- Ponce Family and Youth Clinic Completed Atlanta, Georgia, United States, 30308 United States, Massachusetts Boston Medical Center Withdrawn Boston, Massachusetts, United States, 02118 United States, New York Bellevue Hospital Recruiting New York, New York, United States, 10016 Principal Investigator: William Borkowsky, MD SUNY Upstate Medical University Recruiting Syracuse, New York, United States, 13210 Principal Investigator: Leonard Weiner, MD United States, Tennessee St. Jude Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Principal Investigator: Aditya Gaur, MD United States, Texas University of Texas Health Science Center of Houston Recruiting Houston, Texas, United States, 77030 Principal Investigator: Gloria Heresi, MD Argentina Hospital General de Agudos Dr. Cosme Argerich Recruiting Buenos Aires, Argentina, 1151 Principal Investigator: Diego Cecchini Helios Salud S.A. Recruiting Buenos Aires, Argentina, C1131ACG Principal Investigator: Maria R Bologna Hospital Ramos Mejía Recruiting Buenos Aires, Argentina, C1221ADC DF Principal Investigator: Irene Foradori Fundacion Huesped Recruiting Buenos Aires, Argentina Principal Investigator: Pedro Cahn Thailand Siriraj Hospital Mahidol University Recruiting Bangkok, Krung Thep Maha Nakhon, Thailand Principal Investigator: Kulkanya Chokephaibulkit The HIV NAT Research Collaboration Recruiting Bangkok, Krung Thep Maha Nakhon, Thailand Principal Investigator: Sivaporn Getechompol Srinagarind Hospital Khon Kaen University Recruiting Khon Kaen, Thailand Principal Investigator: Pope Kosalaraksa Less << |
NCT00445146 | HIV Infections | Phase 2 | Completed | - | - |
NCT03631732 | HIV-1 Infection | Phase 3 | Recruiting | August 2020 | - |
NCT00445146 | - | Completed | - | - | |
NCT01814722 | - | Terminated(The trial was termi... More >>nated early due to slow recruitment.) Less << | - | - | |
NCT00000891 | HIV Infections | Phase 2 | Completed | - | United States, Colorado ... More >> Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Illinois Rush Presbyterian - Saint Luke's Med Ctr Chicago, Illinois, United States, 60612 United States, Ohio Case Western Reserve Univ Cleveland, Ohio, United States, 44106 Less << |
NCT00197145 | - | Terminated | - | - | |
NCT01814722 | - | Terminated(The trial was termi... More >>nated early due to slow recruitment.) Less << | - | - | |
NCT00006519 | HIV Infection | Phase 1 | Completed | - | United States, Maryland ... More >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 Less << |
NCT00005673 | Healthy HIV I... More >>nfection Less << | Phase 1 | Completed | - | United States, Maryland ... More >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Less << |
NCT00002378 | HIV Infections | Phase 3 | Completed | - | - |
NCT00006326 | HIV Infections | Not Applicable | Terminated | - | United States, California ... More >> Susan Conner San Diego, California, United States, 92121 Less << |
NCT00002178 | HIV Infections | Phase 3 | Completed | - | United States, California ... More >> Dr Charles Farthing Los Angeles, California, United States, 90048 United States, Massachusetts Community Research Initiative Brookline, Massachusetts, United States, 02445 Less << |
NCT01137981 | - | Recruiting | December 31, 2024 | United States, North Carolina ... More >> GSK Investigational Site Recruiting Wilmington, North Carolina, United States, 28405 Contact: US Clincal Trials Call Center 877-379-3718 Contact: EU Clinical Trials Call Center +44 (0) 20 8990 4466 Less << | |
NCT00002211 | HIV Infections | Not Applicable | Completed | - | United States, New Jersey ... More >> Pharmacia & Upjohn Peapack, New Jersey, United States, 07977 Less << |
NCT00624195 | - | Completed | - | - | |
NCT00002400 | HIV Infections | Not Applicable | Completed | - | United States, New Jersey ... More >> Pharmacia & Upjohn Peapack, New Jersey, United States, 07977 Less << |
NCT00000882 | HIV Infections | Phase 2 | Completed | - | - |
NCT00001094 | HIV Infections | Phase 2 | Withdrawn | - | United States, California ... More >> Willow Clinic Menlo Park, California, United States, 94025 Stanford Univ Med Ctr Stanford, California, United States, 943055107 United States, Colorado Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Florida Univ of Miami School of Medicine Miami, Florida, United States, 331361013 United States, Georgia Emory Univ Atlanta, Georgia, United States, 30308 United States, Hawaii Queens Med Ctr Honolulu, Hawaii, United States, 96816 Univ of Hawaii Honolulu, Hawaii, United States, 96816 United States, Illinois Louis A Weiss Memorial Hosp Chicago, Illinois, United States, 60640 United States, Louisiana Tulane Univ School of Medicine New Orleans, Louisiana, United States, 70112 United States, New York SUNY / Erie County Med Ctr at Buffalo Buffalo, New York, United States, 14215 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 United States, North Carolina Carolinas Med Ctr Charlotte, North Carolina, United States, 28203 Moses H Cone Memorial Hosp Greensboro, North Carolina, United States, 27401 United States, Ohio Univ of Cincinnati Cincinnati, Ohio, United States, 452670405 Ohio State Univ Hosp Clinic Columbus, Ohio, United States, 432101228 United States, Texas Univ of Texas Galveston Galveston, Texas, United States, 775550435 Puerto Rico Univ of Puerto Rico San Juan, Puerto Rico, 009365067 Less << |
NCT00624195 | HIV Infections | Phase 2 Phase 3 | Completed | - | United States, California ... More >> HIV Neurobehavioral Research Center, University of California San Diego San Diego, California, United States, 92103 University of California, San Francisco San Francisco, California, United States, 94110 United States, Maryland Johns Hopkins University- School of Medicine Baltimore, Maryland, United States, 21287 United States, Missouri Washington University St. Louis, Missouri, United States, 63110 United States, New York Mount Sinai Medical Center New York, New York, United States, 10024 Less << |
NCT00002401 | HIV Infections | Not Applicable | Completed | - | United States, New Jersey ... More >> Pharmacia & Upjohn Peapack, New Jersey, United States, 07977 Less << |
NCT00002124 | HIV Infections | Phase 3 | Completed | - | - |
NCT00002420 | HIV Infections | Phase 2 | Terminated | - | United States, California ... More >> Pacific Oaks Med Group Beverly Hills, California, United States, 90211 Less << |
NCT00000810 | HIV Infections | Phase 1 | Completed | - | United States, California ... More >> Stanford CRS Stanford, California, United States, 943055107 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80262 United States, District of Columbia Howard University Hosp., Div. of Infectious Diseases, ACTU Washington, District of Columbia, United States, 20059 United States, Florida Univ. of Miami AIDS CRS Miami, Florida, United States, 331361013 United States, Illinois Northwestern University CRS Chicago, Illinois, United States, 60611 United States, Indiana Indiana Univ. School of Medicine, Infectious Disease Research Clinic Indianapolis, Indiana, United States United States, New York SUNY - Buffalo, Erie County Medical Ctr. Buffalo, New York, United States Univ. of Rochester ACTG CRS Rochester, New York, United States, 14642 United States, North Carolina Unc Aids Crs Chapel Hill, North Carolina, United States United States, Ohio The Ohio State Univ. AIDS CRS Columbus, Ohio, United States Less << |
NCT00002236 | HIV Infections | Not Applicable | Completed | - | United States, California ... More >> AIDS Healthcare Foundation Los Angeles, California, United States, 90027 UCSF AIDS Research Institute San Francisco, California, United States, 94105 United States, New York Saint Luke's - Roosevelt Hosp Ctr New York, New York, United States, 10019 United States, Pennsylvania Anderson Clinical Research Pittsburgh, Pennsylvania, United States, 15213 United States, Tennessee Univ of Tennessee / Div of Infect Dis / Dept of Med Memphis, Tennessee, United States, 38165 United States, Virginia Infectious Disease Physicians Inc Annandale, Virginia, United States, 22203 Less << |
NCT00002312 | HIV Infections | Not Applicable | Completed | - | United States, Michigan ... More >> Bronson Methodist Hosp / Upjohn Research Clinic Kalamazoo, Michigan, United States, 490074949 Less << |
NCT00002123 | HIV Infections | Phase 3 | Completed | - | - |
NCT00823966 | - | Completed | - | - | |
NCT00002210 | HIV Infections | Phase 2 | Completed | - | United States, New Jersey ... More >> Pharmacia & Upjohn Peapack, New Jersey, United States, 07977 Less << |
NCT00000803 | HIV Infections | Phase 2 | Completed | - | - |
NCT02249130 | HIV Infections | Phase 2 | Completed | - | - |
NCT00823966 | - | Completed | - | - | |
NCT00000892 | HIV Infections | Not Applicable | Completed | - | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() | 1mg | 5mg | 10mg |
1 mM 5 mM 10 mM | 2.19mL 0.44mL 0.22mL | 10.95mL 2.19mL 1.10mL | 21.90mL 4.38mL 2.19mL |
Tags: Delavirdine | Sulfamides | NNRTI | HIV | Organic Building Blocks | Anti-Infection | Exosome | 136817-59-9
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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