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Chemical Structure| 135795-51-6 Chemical Structure| 135795-51-6

Structure of 135795-51-6

Chemical Structure| 135795-51-6

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Product Details of [ 135795-51-6 ]

CAS No. :135795-51-6
Formula : C7H9BrN2O
M.W : 217.06
SMILES Code : NC1=C(C)C=C(OC)N=C1Br
MDL No. :MFCD09839257

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Application In Synthesis of [ 135795-51-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 135795-51-6 ]

[ 135795-51-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6635-91-2 ]
  • [ 135795-51-6 ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; bromine; sodium acetate; In water; acetic acid; c 3-Amino-2-bromo-6-methoxy-4-methylpyridine Bromine (4.8 g) was added in one portion to a mixture of <strong>[6635-91-2]5-amino-2-methoxy-4-methylpyridine</strong> (3.9 g) in acetic acid (25 ml) and sodium acetate (4.0 g). The resulting mixture was stirred for 20 min. and then added to a solution of sodium hydroxide (15 g) in water (200 ml). The product was extracted with chloroform, dried (anhydrous magnesium sulfate), concentrated, and purified on a silica gel column (methylene chloride/ethyl acetate, 19:1?4:1) to give 4.5 g of the title compound, suitable for use in the next reaction.
 

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