Home Cart Sign in  
Chemical Structure| 1357094-98-4 Chemical Structure| 1357094-98-4

Structure of 1357094-98-4

Chemical Structure| 1357094-98-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1357094-98-4 ]

CAS No. :1357094-98-4
Formula : C8H8BrN
M.W : 198.06
SMILES Code : BrC1=C(C2CC2)C=CN=C1

Safety of [ 1357094-98-4 ]

Application In Synthesis of [ 1357094-98-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1357094-98-4 ]

[ 1357094-98-4 ] Synthesis Path-Downstream   1~1

  • 1
  • bromo(cyclopropyl)zinc [ No CAS ]
  • [ 13534-90-2 ]
  • [ 1357094-98-4 ]
YieldReaction ConditionsOperation in experiment
51% With tetrakis(triphenylphosphine) palladium(0); at 90℃; for 2.5h;Inert atmosphere; Step I: A solution of cyclopropyl zink bromide (0.5 M, 12 mL, 6.0 mmol) was added to ethyl <strong>[13534-90-2]3,4-dibromopyridine</strong> (1.42 g, 6.0 mmol) and Pd(PPh3)4 (347 mg, 0.6 mmol) and the RM was stirred at 90 Cunder an inert atmosphere for 2.5 h. Subsequently, the volatiles were removed under reduced pressure and the residue was dissolved in water and extracted with CH2CI2. The combined organic layers were dried and the volatiles were removed under reduced pressure. The residue was purified by CC (SiC2, EtOAc/Cy (1:2)) to yield the desired compound (600 mg, 51%).LC-MS (Method 1): m/z [M+H] = 198.1 (MW calc. = 196.98); R1 = 2.6 mm. 1H-NMR (CDCI3): oe = 0.79 (m,2H); 1.15 (m, 2H); 2.20 (m, 1H); 6.72 (d, J = 5.2 H, 1H); 8.85 (d, J = 5.2 Hz, IH); 8.63 (s, 1H). 13C-NMR(CDCI3): oe = 9.7; 15.2; 119.9; 123.9; 148.1; 151.3; 152.1.
 

Historical Records

Technical Information

Categories