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Chemical Structure| 1354555-26-2 Chemical Structure| 1354555-26-2

Structure of 1354555-26-2

Chemical Structure| 1354555-26-2

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Product Details of [ 1354555-26-2 ]

CAS No. :1354555-26-2
Formula : C11H9N3O2
M.W : 215.21
SMILES Code : O=C(C1=CN2C=CC(C#N)=CC2=N1)OCC
MDL No. :MFCD22628059

Safety of [ 1354555-26-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1354555-26-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1354555-26-2 ]

[ 1354555-26-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 70-23-5 ]
  • [ 42182-27-4 ]
  • [ 1354555-26-2 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; at 20℃; Synthesis of 7-cyano-imidazo[l,2-a]pyridine-2-carboxylic acid and 7-carbamoyl- imidazo[l,2-a]pyridine-2-carboxylic acid; To a solution of <strong>[42182-27-4]2-amino-4-cyanopyridine</strong> (4.00 g, 33.6 mmol) in THF (100 mL) add ethyl bromopyruvate (6.55 g, 33.6 mmol). Stir the mixture at rt overnight. A light yellow suspension forms. After filtration and washing with THF, dissolve the light yellow solid in EtOH (50 mL) and heat to reflux for 4 h. Concentrate in vacuo to afford the desired product 7-cyano-imidazo[l,2-a]pyridine-2-carboxylic acid ethyl ester as a solid (6.21 g, 28.9 mmol).
 

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