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Chemical Structure| 13296-21-4 Chemical Structure| 13296-21-4

Structure of 13296-21-4

Chemical Structure| 13296-21-4

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Product Details of [ 13296-21-4 ]

CAS No. :13296-21-4
Formula : C14H16N2O5
M.W : 292.29
SMILES Code : O=C(OCC1=CC=CC=C1)NCCC[C@@H]2NC(OC2=O)=O
MDL No. :MFCD27964741

Safety of [ 13296-21-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 13296-21-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13296-21-4 ]

[ 13296-21-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 32315-10-9 ]
  • [ 16937-91-0 ]
  • [ 13296-21-4 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; at 55℃;Inert atmosphere; epsilon-Benzyloxycarbonyl ornithine N-Carboxyanhydride (ZOrn-NCA) was synthesized by following a literature procedure [44]. Briefly, ZOrn (5.00 g, 18.7 mmol) and triphosgene (3.50 g, 11.8 mmol) was suspended in 100 mL of dry THF under argon. The mixture was stirred in a 55 C oil bath until the cloudy solution turned clear. The solution was precipitated by addition of excess petroleum ether. The precipitate was collected by filtration and purified by recrystallization from ethyl acetate and petroleum ether. 1H NMR (300 MHz, CDCl3, delta): 7.35 (br s, C6H5), 5.09 (s, C6H5CH2), 4.32 (s, COCHNHCOO), 3.23 (s, CH2CH2CH2NHCOO), 1.95-1.61 (m, CHCH2CH2CH2NH).
 

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