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Chemical Structure| 1313709-87-3 Chemical Structure| 1313709-87-3

Structure of 1313709-87-3

Chemical Structure| 1313709-87-3

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Product Details of [ 1313709-87-3 ]

CAS No. :1313709-87-3
Formula : C7H8N4
M.W : 148.17
SMILES Code : NC1=NNC2=C1C=NC(C)=C2
MDL No. :MFCD24644400

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Application In Synthesis of [ 1313709-87-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1313709-87-3 ]

[ 1313709-87-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 38875-76-2 ]
  • [ 1313709-87-3 ]
YieldReaction ConditionsOperation in experiment
64% With hydrazine hydrate; In butan-1-ol; for 12h;Reflux; Inert atmosphere; To a mixture of compound 4-chloro-6- methylnicotinonitrile (8.0 g, 52.6 mmol, 1.0 eq) in n-butanol (80 mL) was added hydrazine hydrate (7.9 g, 158 mmol, 3.0 eq), the mixture was heated to reflux under nitrogen for 12 h. The reaction mixture was allowed to cool to room temperature, the solid was collected by filtration and washed with ethyl acetate (30 mL> 2). Dried to give compound 3-amino-6-methyl-lH- pyrazolo[4,3-c]pyridine (5.0 g, 64%). NMR (300 MHz, DMSO- e) delta 11.61 (br, 1H), 8.80 (s, 1H), 6.97 (s, 1H), 5.69 (s, 2H), 2.46 (s, 3H). ESI-MS (m/z): 149.0 (M+H)+.
 

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