Home Cart Sign in  
Chemical Structure| 128460-74-2 Chemical Structure| 128460-74-2

Structure of 128460-74-2

Chemical Structure| 128460-74-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 128460-74-2 ]

CAS No. :128460-74-2
Formula : C15H14O2
M.W : 226.27
SMILES Code : O=C(C1=CC(C2=CC=CC(C)=C2)=CC=C1)OC
MDL No. :MFCD05979105
InChI Key :CVGLGEBUFGMUDD-UHFFFAOYSA-N
Pubchem ID :1392448

Safety of [ 128460-74-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P363-P403+P233-P405-P501

Application In Synthesis of [ 128460-74-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 128460-74-2 ]

[ 128460-74-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2905-65-9 ]
  • [ 17933-03-8 ]
  • [ 128460-74-2 ]
YieldReaction ConditionsOperation in experiment
94% With potassium phosphate; 3-(dicyclohexylphosphino)-2-(2,6-dimethoxyphenyl)-1-methyl-1H-indole; palladium diacetate; palladium; In 1,4-dioxane; at 100℃; for 2h;Schlenk technique; Inert atmosphere; General procedure: Palladium acetate (0.0022 g, 0.01 mmol), a phosphine ligand (palladium: phosphine ligand ratio of 1.0 mol%: 4 mol%) and A teflon-coated magnetic stir bar was placed in a 20 mL Schlenk tube, the system replaced with nitrogen, then 10 mL of freshly distilled dioxane was added and they were stirred for 10 minutes to form the palladium complex. Meanwhile, a chloro-aromatic hydrocarbon (1.0 mmol), substituted phenylboronic acid (1.5 mmol), potassium phosphate (3.0 mmol) and a Teflon-coated magnetic stir bar were placed in another 20 mL Schlenk tube. After 3 cycles of vacuum nitrogen back and forth, the appropriate amount (eg, 0.1 mL, 0.01 mol%) of the stock palladium complex solution was withdrawn by means of a gas-tight syringe to a column containing the chloroarene (1.0 mmol), substituted phenylboronic acid 1.5 mmol), potassium phosphate (3.0 mmol) and a teflon-coated magnetic stir bar and a nitrogen-protected Schlenk tube. Finally, a corresponding amount of freshly distilled dioxane was added (final amount of solvent was 3.0 mL). The Schlenk tube was then placed in an oil bath preheated to 100 C for 2-24 hours, as shown in the reaction scheme below. After the reaction was completed, the reaction tube was cooled to room temperature, the reaction was stopped, ethyl acetate (6.0 mL) and water (2.0 mL) were added to the system, and the organic layer was subjected to gas chromatographic analysis. Thereafter, the mixture is further extracted with about 10 mL of ethyl acetate in three to four times, and then the organic phases are combined. After the organic phase is concentrated under reduced pressure, the concentrate is purified by silica gel column chromatography to obtain a cross-coupled product.
 

Historical Records

Technical Information

Categories