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Chemical Structure| 1261242-16-3 Chemical Structure| 1261242-16-3

Structure of 1261242-16-3

Chemical Structure| 1261242-16-3

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Product Details of [ 1261242-16-3 ]

CAS No. :1261242-16-3
Formula : C13H19N3O4S
M.W : 313.37
SMILES Code : O=C(OCC1=CC=CC=C1)NCCN(CCN2C)S2(=O)=O

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Application In Synthesis of [ 1261242-16-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1261242-16-3 ]

[ 1261242-16-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 134307-72-5 ]
  • [ 67104-97-6 ]
  • [ 1261242-16-3 ]
YieldReaction ConditionsOperation in experiment
42.9% Under nitrogen atmosphere, the compound 6a (0.856 g, 6.26 mmol) was dissolved in 5 mL of anhydrous DMSO,and 60% NaH (0.282 g, 11.8 mmol) was slowly added dropwise at 0C. The temperature was raised to room temperature,and then the solution was stirred for 1 hour. 2-(((benzyloxy)carbonyl)amino)ethyl methane sulfonate (1.5 g, 5.83 mmol)was slowly added dropwise at 0 C, and then stirred at room temperature for 5 hours. After the reaction was completed,extraction was performed with ethyl acetate, and an organic solvent layer was dried over MgSO4. Filtration was performedto remove the solvent, and a residue was purified by column chromatography (EtOAc) to obtain a compound 7a (0.82 g). Sticky oil (42.9%). 1H-NMR (CDCl3, 300MHz) delta7.36-7.30 (m, 5H), 5.19 (bs, 1H), 5.10 (s, 2H), 3.46 (q, 2H, J = 5.9 Hz), 3.36-3.26 (m, 4H), 3.20 (t, 2H, J = 6.0 Hz). LC-MS: Predicted value calculated with respect to C13H19N3O4S m/z: 313. Measured value: 314(M+1)+.
 

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