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Chemical Structure| 1260599-41-4 Chemical Structure| 1260599-41-4

Structure of 1260599-41-4

Chemical Structure| 1260599-41-4

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Product Details of [ 1260599-41-4 ]

CAS No. :1260599-41-4
Formula : C8H16BrN3OSi
M.W : 278.22
SMILES Code : C[Si](CCOCN1N=C(Br)N=C1)(C)C

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Application In Synthesis of [ 1260599-41-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1260599-41-4 ]

[ 1260599-41-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7343-33-1 ]
  • [ 76513-69-4 ]
  • [ 1260599-41-4 ]
YieldReaction ConditionsOperation in experiment
Sodium hydride (1.2eq) was added to a solution of 3-bromo-lH-[l,2,4]triazole (leq) in dry DMF (2.3ml/mmol) at 00C and under an atmosphere of nitrogen The solution was stirred at 00C for 20min, then, SEM-Cl (1.2eq) was added. The mixture was stirred at room temperature overnight and diluted with H2O and ethyl acetate. The organic layers was washed with H2O then brine, dried on anhydrous Na2SO4, filtered and concentrated in vacuum to give the titled compound. Crude compound 3- bromo-l-(2-trimethylsilanyl-ethoxymethyl)-lH-[l,2,4]triazole was engaged in step 2 without purification. IH-NMR (CDCl3): delta (ppm) 0.00 (t, 9H); 0.92 (t, 2H); 3.64 (t, 2H); 5.44 (s, 2H); 8.13 (s, IH)
 

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