Home Cart Sign in  
Chemical Structure| 1256337-01-5 Chemical Structure| 1256337-01-5

Structure of 1256337-01-5

Chemical Structure| 1256337-01-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1256337-01-5 ]

CAS No. :1256337-01-5
Formula : C14H20N2O4
M.W : 280.32
SMILES Code : O=C(OCC)CC1=CC=C(NC(OC(C)(C)C)=O)N=C1
MDL No. :MFCD26399506

Safety of [ 1256337-01-5 ]

Application In Synthesis of [ 1256337-01-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1256337-01-5 ]

[ 1256337-01-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4248-19-5 ]
  • [ 197376-47-9 ]
  • [ 1256337-01-5 ]
YieldReaction ConditionsOperation in experiment
With caesium carbonate;tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; In tetrahydrofuran; for 20h;Heating; Inert atmosphere; Reflux; Step 3. Synthesis of (beta-tert-butoxycarbonylamino-pyrjdin-S-yO-acetic acid ethyl ester. A 500 ml round-bottom-flask was charged with 2-chloropyndiotan- 3-yl) acetic acid ethyl ester (6 8 g, 34 0 mmol), tert-butyl carbamate (12 4 g, 105 mmol), 9,9-diotamethyl-4,5-biotas(diotaphenylphosphiotano)xanthene (4 2 g, 7 25 mmol), triotas(diotabenzyliotadeneacetone)diotapal.adiotaum (3 29 g, 3 59 mmol) cesium carbonate (16 9 g 51 87 mmol) and THF (165 mL) The mixture was heated and refluxed under argon for 20 hours Upon cooling, the reaction was quenched with 10% ammonium acetate solution and extracted with ethyl acetate The combined organic extracts were washed with water, brine dried and concentrated The residue was purified by silica gel chromatography eluted using a gradient of 2/98(v/v) EtOAc/hexanes to 10/90 (v/v) EtOAc/hexanes to afford 14 g of crude product ESI-MS m/z 225 (MH-C4He)+
 

Historical Records

Technical Information

Categories