Home Cart Sign in  
Chemical Structure| 1253188-91-8 Chemical Structure| 1253188-91-8

Structure of 1253188-91-8

Chemical Structure| 1253188-91-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1253188-91-8 ]

CAS No. :1253188-91-8
Formula : C8H6F3IO
M.W : 302.03
SMILES Code : OCC1=CC=C(I)C=C1C(F)(F)F
MDL No. :MFCD15528742

Safety of [ 1253188-91-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 1253188-91-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1253188-91-8 ]

[ 1253188-91-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 954815-11-3 ]
  • [ 1253188-91-8 ]
YieldReaction ConditionsOperation in experiment
To a solution of <strong>[954815-11-3]4-iodo-2-(trifluoromethyl)benzoic acid</strong> (for a preparation see Intermediate 31 )(16.7 g, 52.8 mmol) in THF (150 ml) at ambient temperature under nitrogen was added 1.0 M borane-tetrahydrofuran complex (100 ml, 100 mmol, Aldrich) dropwise. The solution was heated to 80 0C for 1.5 h. To the solution at ambient temperature was added methanol (75 ml) and then heated to 80 0C for 1 h. The solvent was removed in vacuo to leave a mobile oil. The residue was partitioned between ethyl acetate (200 ml) and 2 N aqueous HCI (100 ml). The phases were separated and the organic phase washed with 2 N aqueous sodium hydroxide (100 ml), brine (50 ml), then dried (MgSO4), filtered and the solvent removed in vacuo to give [4-iodo-2-(trifluoromethyl)phenyl]methanol as a pale brown solid (14.8 g).
 

Historical Records