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Chemical Structure| 1246349-99-4 Chemical Structure| 1246349-99-4

Structure of 1246349-99-4

Chemical Structure| 1246349-99-4

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Product Details of [ 1246349-99-4 ]

CAS No. :1246349-99-4
Formula : C6H3BrClN3
M.W : 232.47
SMILES Code : ClC1=NC=CC2=C1C(Br)=NN2
MDL No. :MFCD18205978
InChI Key :CTZAGTLJGOBGEJ-UHFFFAOYSA-N
Pubchem ID :59619102

Safety of [ 1246349-99-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P301+P310
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 1246349-99-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1246349-99-4 ]

[ 1246349-99-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 871836-51-0 ]
  • [ 1246349-99-4 ]
YieldReaction ConditionsOperation in experiment
81% With N-Bromosuccinimide; In acetonitrile; for 3h;Reflux; Intermediate 153-Bromo-<strong>[871836-51-0]4-chloro-1H-pyrazolo[4,3-c]pyridine</strong>N-bromosuccinimide (1.87 g, 10.5 mmol) was added to a solution of Intermediate 11 (1.61 g, 10.5 mmol) in acetonitrile (50 ml), and the mixture was heated to reflux for 3 h. The solvents were evaporated and DCM (60 ml) was added to the crude solid and the mixture stirred at r.t. for 30 min. The beige solid was filtered off, washed with DCM, then dried under vacuum (1.98 g, 81percent). 1H NMR (400 MHz, DMSO-c/6) delta ppm 7.69 (d, J=6.0 Hz, 1 H), 8.22 (d, J=6.0 Hz, 1 H); m/z (ES+APCI)+: 232 / 234 / 236 [M + H]+.
 

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Technical Information

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Related Functional Groups of
[ 1246349-99-4 ]

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Related Parent Nucleus of
[ 1246349-99-4 ]

Other Aromatic Heterocycles

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