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Chemical Structure| 122307-44-2 Chemical Structure| 122307-44-2

Structure of 122307-44-2

Chemical Structure| 122307-44-2

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Product Details of [ 122307-44-2 ]

CAS No. :122307-44-2
Formula : C6H5BrFN
M.W : 190.01
SMILES Code : FC1=CC=CN=C1CBr
MDL No. :MFCD11520698
InChI Key :NBVWYLPHVYSPEI-UHFFFAOYSA-N
Pubchem ID :21613173

Safety of [ 122307-44-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 122307-44-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 122307-44-2 ]

[ 122307-44-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 31181-79-0 ]
  • [ 122307-44-2 ]
YieldReaction ConditionsOperation in experiment
11% With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 20℃; for 22h;Inert atmosphere; A solution of 285 mg (2.242 mmol) (3-fluoropyridin-2-yl) -methanol (CAS: 31181-79-0) in dry dichloromethane (9 ml) under an argon atmosphere in an ice water bath with 882 mg (3:36 mmol) of triphenylphosphine and 1.12 of g (3:36 mmol) of carbon tetrabromide was added.The reaction mixture was stirred for 22 hours at room temperature.The solvent was evaporated and the residue was purified by flash chromatography using a prepacked silica gel cartridge: purified (mobile phase cyclohexane-ethyl acetate, gradient 15percent to 30percent)) to give 156 mg (11percent yield, 98percent pure) of the title compound received.
 

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