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Chemical Structure| 1207623-95-7 Chemical Structure| 1207623-95-7

Structure of 1207623-95-7

Chemical Structure| 1207623-95-7

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Product Details of [ 1207623-95-7 ]

CAS No. :1207623-95-7
Formula : C14H17BFNO2
M.W : 261.10
SMILES Code : CC1(C)C(C)(C)OB(C2=C(F)C3=C(NC=C3)C=C2)O1
MDL No. :MFCD18383899
InChI Key :REHTYXFUXRZYKP-UHFFFAOYSA-N
Pubchem ID :67078314

Safety of [ 1207623-95-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1207623-95-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1207623-95-7 ]

[ 1207623-95-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 73183-34-3 ]
  • [ 344790-96-1 ]
  • [ 1207623-95-7 ]
YieldReaction ConditionsOperation in experiment
With potassium acetate;dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In N,N-dimethyl-formamide; at 100℃;Inert atmosphere; <strong>[344790-96-1]5-Bromo-4-fluoro-1H-indole</strong> obtained by the method described in Eur. J. Org. Chem. 2956-2969, 2006 (793 mg) was dissolved in N,N-dimethylformamide (30 ml), and bis(pinacolato)diboron (1.88 g), potassium acetate (1.82 g) and a [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) chloride-dichloromethane complex (151 mg) were added. The mixture was stirred with heating under nitrogen atmosphere at 100 C. overnight. The reaction solution was cooled to room temperature and then concentrated under reduced pressure. The residue was purified by silica gel column chromatography (developed with ethyl acetate-hexane). The resulting colorless oil was slurry washed with hexane to give the title compound (481 mg) as a colorless solid.MS (EI) m/z: 261M+.1H-NMR (CDCl3) delta: 1.38 (12H, s), 6.65-6.68 (1H, m), 7.14-7.17 (1H, m), 7.18 (1H, s), 7.51 (1H, dd, J=8.3, 5.5 Hz), 8.27 (1H, brs).
 

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