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Chemical Structure| 1205537-34-3 Chemical Structure| 1205537-34-3

Structure of 1205537-34-3

Chemical Structure| 1205537-34-3

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Product Details of [ 1205537-34-3 ]

CAS No. :1205537-34-3
Formula : C16H22ClN5O2
M.W : 351.83
SMILES Code : O=C(N1CCC(N2N=C(C)C3=C(Cl)N=CN=C32)CC1)OC(C)(C)C
MDL No. :MFCD27992039

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Application In Synthesis of [ 1205537-34-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1205537-34-3 ]

[ 1205537-34-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1196486-69-7 ]
  • [ 60025-06-1 ]
  • [ 1205537-34-3 ]
YieldReaction ConditionsOperation in experiment
12% With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 - 60℃; for 21.5h;Inert atmosphere; Step 2 - Synthesis of Compound 13B; Compound 13A (860 mg) was dissolved in DMF (5 mL) and to the resulting solution was added DIPEA (1.1 mL, 1.4 eq), followed by compound 12B (1.36 g, 1.4 eq). The resulting reaction was allowed to stir at room temperature under nitrogen atmosphere for 2.5 hours, then the reaction mixture was heated at 60 0C and allowed to stir at this temperature for an additional 19 hours. The reaction mixture was cooled to room temperature and concentrated in vacuo to provide a brown oily residue which was purified using flash column chromatography on silica gel to provide compound 13B (192 mg, 12%).
 

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