Home Cart Sign in  
Chemical Structure| 1169698-47-8 Chemical Structure| 1169698-47-8

Structure of 1169698-47-8

Chemical Structure| 1169698-47-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1169698-47-8 ]

CAS No. :1169698-47-8
Formula : C14H16ClN5
M.W : 289.76
SMILES Code : NC1=NC=C(C2=C(Cl)C=NC=C2)C(NC3CCCC3)=N1
MDL No. :MFCD23702041

Safety of [ 1169698-47-8 ]

Application In Synthesis of [ 1169698-47-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1169698-47-8 ]

[ 1169698-47-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1169698-46-7 ]
  • [ 458532-98-4 ]
  • [ 1169698-47-8 ]
YieldReaction ConditionsOperation in experiment
80% With sodium carbonate;trans-bis(triphenylphosphine)palladium dichloride; In 1,4-dioxane; water; at 120℃; for 22h; To a solution of 2 (2.57 g, 10.0 mmol) in dioxane (75 mL) were added <strong>[458532-98-4]3-chloropyridine-4-boronic acid</strong> (4.72 g, 10.0 mmol), trans- dichlorobis(triphenylphosphine)-palladium(II)(702 mg, 1.0 mmol), and sodium carbonate (3.82 g, 36 mmol, in 36 mL of water). The mixture thus obtained was purged with N2 for 10 min and heated at 12O0C in a sealed tube for 22 h. The reaction mixture was diluted with water and the product was extracted with chloroform. The organic layers were dried (MgSO4) and concentrated. The residue was purified by flash chromatography on silica gel eluting with 2.5% methanol in dichloromethane to give the title compound (3) as a white solid (2.31g, 80%). 1H NMR (500 MHz, DMSO-(I6) delta 8.64 (IH, s), 8.50 (IH, d, J = 4.9 Hz), 7.51 (IH, s), 7.34 (IH, d, IH, J = 4.9 Hz), 6.21 (2H, d, IH, br s), 5.97 (IH, d, J = 7.6 Hz), 4.43 (1 H, p, J = 7.4Hz), 1.84 (2H, m), 1.62 (2H, m), 1.40-1.49 (4H, m) ppm; LCMS-ESI (POS), M/Z, M+l : Found 290.0, Calculated 290.1.
 

Historical Records

Technical Information

Categories