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Chemical Structure| 1159736-58-9 Chemical Structure| 1159736-58-9

Structure of 1159736-58-9

Chemical Structure| 1159736-58-9

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Product Details of [ 1159736-58-9 ]

CAS No. :1159736-58-9
Formula : C8H9IN2
M.W : 260.07
SMILES Code : NC1(C2=NC=C(I)C=C2)CC1

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Application In Synthesis of [ 1159736-58-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1159736-58-9 ]

[ 1159736-58-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 925-90-6 ]
  • [ 41960-47-8 ]
  • [ 1159736-58-9 ]
YieldReaction ConditionsOperation in experiment
To a solution of <strong>[41960-47-8]5-iodo-pyridine-2-carbonitrile</strong> (1.0 g, 8.1 mmol) in dry THF (50 mL) was added titanium(IV) isopropoxide (5.2 mL, 18 mmol). EtMgBr (3.0M in Et2O, 10 mL, 32 mmol) was then added drop wise. The reaction mixture was stirred for 23 h, then diluted with water (100 mL) and IN HCl (5 mL), and stirred for 5 minutes. The mixture was filtered and the filtrate was concentrated in-vacuo to afford 430 mg of the title compound which was used without further purification.
 

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