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Chemical Structure| 1152958-56-9 Chemical Structure| 1152958-56-9

Structure of 1152958-56-9

Chemical Structure| 1152958-56-9

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Product Details of [ 1152958-56-9 ]

CAS No. :1152958-56-9
Formula : C11H7N3O
M.W : 197.19
SMILES Code : N#CC1=CC=C(N2N=CC(C=O)=C2)C=C1

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Application In Synthesis of [ 1152958-56-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1152958-56-9 ]

[ 1152958-56-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1194-02-1 ]
  • [ 35344-95-7 ]
  • [ 1152958-56-9 ]
YieldReaction ConditionsOperation in experiment
With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 60℃; for 6h;Inert atmosphere; To a mixture of 4-fluorobenzonitrile (2.49 g, 20.6 mmol) and 4-formylpyrazole (1.98 g, 20.6 mmo) in 50 mL of DMF at 0 0C was added 95percent sodium hydride (0.54 g, 22.7 mmol) under nitrogen. The mixture was heated to 60 0C for 6 hours and cooled to room temperature, Water was added carefully and the mixture was then extracted with ethyl acetate. The combined extracts were washed with water and brine, and then dried over sodium sulfate, filtered, and concentrated in vacuo to provide crude 4~(4-formyMH-pyrazol-l-yl)benzonitrile.
 

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