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Chemical Structure| 1141-35-1 Chemical Structure| 1141-35-1

Structure of 1141-35-1

Chemical Structure| 1141-35-1

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Product Details of [ 1141-35-1 ]

CAS No. :1141-35-1
Formula : C13H8ClNO
M.W : 229.66
SMILES Code : ClC1=CC=C(C2=NC3=CC=CC=C3O2)C=C1
MDL No. :MFCD00453917
InChI Key :NTMAGNRMERGORC-UHFFFAOYSA-N
Pubchem ID :14355

Safety of [ 1141-35-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 1141-35-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1141-35-1 ]

[ 1141-35-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 273-53-0 ]
  • [ 14752-66-0 ]
  • [ 1141-35-1 ]
YieldReaction ConditionsOperation in experiment
83% General procedure: Under nitrogen atmosphere, a sealable reaction tube equipped with a magnetic stirrer bar was charged with azole (0.50 mmol), sodium arylsulfinate (1.0 mmol), Pd(OAc)2 (0.025 mmol), Cu(OAc)2 (1.0 mmol), CF3COOH (0.50 mmol), and dimethylglycol (2.0 mL). The rubber septum was then replaced by a Teflon-coated screw cap, and the reaction vessel placed in an oil bath at 120 C for 24 h. After the reaction was completed, it was cooled to room temperature and the mixture was treated with K2CO3 solution (1.0 mol/L, 3.0 mL), then extracted with ethyl acetate. The resulting solution was dried by Na2SO4 then concentrated under reduced pressure. The residue was purified by flash chromatography on silica gel (eluant: petroleum ether/ethyl acetate=12:1, v/v) to give the desired product.
 

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