Home Cart Sign in  
Chemical Structure| 1111640-52-8 Chemical Structure| 1111640-52-8

Structure of 1111640-52-8

Chemical Structure| 1111640-52-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1111640-52-8 ]

CAS No. :1111640-52-8
Formula : C9H14F3NO5
M.W : 273.21
SMILES Code : O=C(C1CNCCO1)OCC.O=C(O)C(F)(F)F
MDL No. :MFCD11973835

Safety of [ 1111640-52-8 ]

Application In Synthesis of [ 1111640-52-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1111640-52-8 ]

[ 1111640-52-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 135072-32-1 ]
  • [ 76-05-1 ]
  • [ 1111640-52-8 ]
YieldReaction ConditionsOperation in experiment
With hydrogen;palladium on activated charcoal; In ethanol; at 25℃; for 4h; Intermediate 16: Ethyl morpholine-2-carboxylate trifluoroacetate salt. A suspension of ethyl 4-(phenylmethyl)-2-morpholinecarboxylate (prepared according to procedure described on J. of Med. Chem. 1993, vol. 36, No. 6, 683-689) (900 mg, 3.61 mmol), TFA (0.278 ml_, 3.61 mmol), and Pd/C (150 mg, 1.410 mmol) in EtOH (15 ml), was degassed four times under nitrogen and then degassed three times under H2. The reaction mixture was left stirring under H2 at 250C for 4h. MS monitor showed the reaction was complete.The reaction mixture was filtered and solvent was removed to give the title compound (950 mg); m/z (ES): 160 [M+H]+; 1H NMR (400 MHz, CHLOROFORM-d) delta ppm 10.5(bs, 1 H) 4.53- 4.50 (m, 1 H) 4.33-4.27 (q, 2 H) 4.22-4.19 (m, 1 H) 4.05-3.98 (m, 1 H) 3.79-3.74 (m, 1 H) 3.65-3.61 (m, 1 H) 3.34-3.31 (m, 1 H) 3.24-3.18 (m, 1 H) 1.35-1.32 (t, 2 H) 1.29-1.25 (t, 1 H).
 

Historical Records

Technical Information

Categories

Similar Product of
[ 1111640-52-8 ]

Chemical Structure| 135072-31-0

A841899 [135072-31-0]

Ethyl 2-Morpholinecarboxylate Hydrochloride

Reason: Different form