Alternatived Products of [ 1111637-72-9 ] Product Details of [ 1111637-72-9 ]
CAS No. : | 1111637-72-9 | MDL No. : | MFCD12964547 |
Formula : |
C8H11BN2O3 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | - |
M.W : |
194.00
| Pubchem ID : | - |
Synonyms : | |
Safety of [ 1111637-72-9 ]
Application In Synthesis of [ 1111637-72-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1111637-72-9 ]
- 1
- [ 142404-82-8 ]
- [ 1111637-72-9 ]
Yield | Reaction Conditions | Operation in experiment |
| | Preparation of 6-acetamido-4-methylpyridin-3-ylboronic acid (73)To a stirred solution of the 2-acetylamino-5-bromo-4-methylpyridine (1.858g, 8.11 mmol) and boron isopropoxide (7.5ml, 32.4mmol) in THF cooled to -780C was added n-butyl lithium (4.1 ml, 41mmol of 10 M soln in hexanes). After 1 hour at -780C, the reaction was quenched with water and warmed to room temperature. THF was removed under reduced pressure. Added 2N HCI until a precipitate developed. Filtered and washed with a minimal amount of water and dried under vacuum. 1 H NMR (400 MHz, DMSO-d6) d ppm 2.07 (s, 3 H) 2.39 (s, 3 H) 7.84 (s, 1 H) 8.09 (s, 2 H) 8.33 (s, 1 H) 10.36 (s, 1 H). |