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Chemical Structure| 1110766-97-6 Chemical Structure| 1110766-97-6

Structure of Lusutrombopag
CAS No.: 1110766-97-6

Chemical Structure| 1110766-97-6

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Lusutrombopag is an agonist of bioavailablethrombopoietin (TPO) receptor that is used to treat chronic liver disease.

Synonyms: S-888711; Mulpleta

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Product Details of Lusutrombopag

CAS No. :1110766-97-6
Formula : C29H32Cl2N2O5S
M.W : 591.55
SMILES Code : O=C(O)/C(C)=C/C1=C(Cl)C=C(C(NC2=NC(C3=CC=CC([C@@H](OCCCCCC)C)=C3OC)=CS2)=O)C=C1Cl
Synonyms :
S-888711; Mulpleta
MDL No. :MFCD28502075
InChI Key :NOZIJMHMKORZBA-KJCUYJGMSA-N
Pubchem ID :49843517

Safety of Lusutrombopag

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT06426043 Aplastic Anemia PHASE4 NOT_YET_RECRUITING 2025-08-25 Peking Union Medical College H... More >>ospital, Beijing, Beijing, 100730, China Less <<
NCT01129024 Immune Thrombocytopenia PHASE2 TERMINATED 2011-06-30 Investigator, Anaheim, Califor... More >>nia, 92801, United States|Investigator, Los Angeles, California, 90272, United States|Investigator, Washington, District of Columbia, 20007, United States|Investigator, Boynton Beach, Florida, 33426, United States|Investigator, Jacksonville, Florida, 32207, United States|Investigator, Atlanta, Georgia, 30341, United States|Investigator, Riverdale, Georgia, 30274, United States|Investigator, Metairie, Louisiana, 70006, United States|Investigator, Bethesda, Maryland, 20817, United States|Investigator, Boston, Massachusetts, 02114, United States|Investigator, Jefferson City, Missouri, 65109, United States|Investigator, Kansas City, Missouri, 64131, United States|Investigator, New Brunswick, New Jersey, 08903, United States|Investigator, New York, New York, 10021, United States|Investigator, New York, New York, 10029, United States|Investigator, Cleveland, Ohio, 44106, United States|Investigator, San Antonio, Texas, 78229, United States|Investigator, Salt Lake City, Utah, 84132, United States|Investigator, Seattle, Washington, 98109, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.69mL

0.34mL

0.17mL

8.45mL

1.69mL

0.85mL

16.90mL

3.38mL

1.69mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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