Home Cart Sign in  
Chemical Structure| 1108723-65-4 Chemical Structure| 1108723-65-4

Structure of 1108723-65-4

Chemical Structure| 1108723-65-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1108723-65-4 ]

CAS No. :1108723-65-4
Formula : C15H21NO2
M.W : 247.33
SMILES Code : CC(C)(OC(NCC1=CC(C2CC2)=CC=C1)=O)C

Safety of [ 1108723-65-4 ]

Application In Synthesis of [ 1108723-65-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1108723-65-4 ]

[ 1108723-65-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 171663-13-1 ]
  • [ 411235-57-9 ]
  • [ 1108723-65-4 ]
YieldReaction ConditionsOperation in experiment
93% With potassium phosphate;palladium diacetate; tricyclohexylphosphine; In water; toluene; at 100℃; for 3h; Example 1.1.22: (3-cyclopropylphenyl)methanamine; To a solution of <strong>[171663-13-1]tert-butyl 3-bromobenzylcarbamate</strong> (572 mg, 2 mmol), cyclopropyl boronic acid (223 mg, 2.6 mmol), potassium phosphate (1.49 g, 7.0 mmol) and tricyclohexyl phosphine (56 mg, 0.2 mmol)in toluene (9 mL) and water (0.45 mL) under a nitrogen atmosphere was added palladium acetate (22mg, 0.1 mmol). The mixture was heated at 1000C for 3h and then cooled to rt. Water (20 mL) was added and the mixture extracted with EtOAc (2x30 mL), the combined organic extracts were washed with brine (20 mL), dried over Na2SO4 and concentrated in vacuo. Crude product was purified by column chromatography (15% EtOAc in hexanes) afforded tert-butyl 3-cyclopropylbenzylcarbamate as a colorless oil in 93% yield. (3-cyclopropylphenyl)methanamine was then generated by removing the Boc protecting group by treatment with HCl (in methanol or dioxane) or trifluoroacetic acid in dichloromethane.
 

Historical Records